<i>Introduction</i>: Systemic lupus erythematosus (SLE) reduces the health-related quality of life (HRQoL), even during periods of disease quiescence. We investigated whether subclinical inflammation as reflected by cytokine levels is linked with reduced HRQoL. Methods: A cross-sectional study of SLE patients (<i>n</i> = 52, mean age 47.3, 86.5% female) who completed a Short Form Health Survey-36 ...